Vibrant Gastro: Leveraging Technology to Help Constipation Patients Live Life to the Fullest

Who is Vibrant Gastro?

Vibrant Gastro is the pioneer of the Synchronized Activation Method™, a first-in-class drug-free technology that is the driving force behind the Vibrant System. This state-of-the-art system utilizes pre-programmed micro-vibrations to stimulate the colon mechanically, improving natural colonic motility.

Vibrant is indicated for the treatment of adults with chronic idiopathic constipation (CIC) who have not experienced relief of their bowel symptoms by using laxative therapies at the recommended dosage for at least 1 month.

The Synchronized Activation Method™ opens the door to future indications for data-driven, personalized treatments that leverage the gut-brain connection via the enteric nervous system (ENS) pathway.

Our Mission

Create drug-free treatments that enable millions of constipation patients to live more enjoyable lives via new products that synchronize and activate the gut-brain connection to provide control over their bodies and predictable symptom relief.

Vibrant has completed the HIPAA Compliance exercise and has implemented all necessary controls and protections for all information collections (January 30, 2022).

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Executive Leadership Team

  • Asaf has over 20 years of experience in business development, upstream marketing, and finance roles. He has hands-on expertise in growing successful businesses by creating strategies, leading business development activities, and developing cutting-edge products. He has held senior positions in public and private medical device and biotechnology companies, including Johnson & Johnson, Omrix Biopharmaceuticals, and Lumenis. Asaf holds a Bachelor of Arts degree in Economics and Business Administration from the University of Haifa.

  • Mark has three decades of experience leading strategy, promoting market access, and aligning value-based health care and population health in inpatient hospital and outpatient surgical settings. He previously served as senior director for Smith+Nephew and has led strategic market access and reimbursement efforts for companies including Mölnlycke, US and Johnson & Johnson. He received his MBA from La Salle University and his bachelor of science from Eastern Connecticut State University.

  • Having served as GM of pharmaceutical manufacturing plants in Israel and in Europe, Martha has extensive experience in global operations, processes, local/global connections, and human resources. She holds an MS in biochemical engineering and a PhD in Immunology.

    Martha has extensive experience in building processes, creating local and global connections, and managing human resources.

    Martha holds a Master’s degree in biochemical engineering and a PhD in immunology.

  • Doug has nearly 30 years’ experience in senior commercial leadership with a proven impact as a growth driver. He previously served as business director at Alnylam Pharmaceuticals, with prior efforts at Flexion Therapeutics, Takeda Pharmaceuticals, Bayer Pharmaceuticals, and others. He received his bachelor of science from Indiana University Bloomington.

  • Eli has 15 years of experience as CFO in both large and international organizations and start-ups, including Vocaltec, Cimastron, and IFN Systems Ltd. He is a CPA with a BA in accounting and economics from Tel Aviv University, and an MA in law from Bar-Ilan University in Israel.

  • Shai brings more than 10 years of experience in R&D management in the biomedical arena. He has led the R&D teams at various companies including Ion Medical, Ortospace, and Contipi.

  • Lior led Vibrant Gastro as the CEO & Co-Founder since 2010, acting as the company`s clinical manager, inventor and co-designer of Vibrant holistic system. Lior brings 35 years of experience in the start-up leadership in Med-Tech and Hi-Tech companies.

  • An experienced product executive with a vast software and mobile background, Uri has experience in digital mobile products and AI. He is an industrial engineer from the Technion and an MBA graduate from IDC.

Scientific Advisors


  • Professor of Medicine

    Digestive health expert who helped launch the Augusta University Digestive Health Center

    • Excelled as an outstanding researcher, distinguished educator, and Master Clinician

    • Research focuses on the pathophysiology and treatment of IBS, constipation, and fecal incontinence and visceral pain, particularly esophageal chest pain


  • Professor of Medicine

    • VP of the American College of Gastroenterology and a past editor-in-chief of The American Journal of Gastroenterology

    • Published over 500 articles, 6 books, and several monographs

    • Received a variety of honors and awards from medical and gastroenterological societies and universities throughout the world


  • Professor of Medicine

    • Associate professor of medicine at Harvard Medical School and gastroenterologist in practice

    • Focus on motility disorders, IBS, swallowing issues, endoscopy, colon cancer screening, and GERD

    • Member of American Board of Internal Medicine and the American Board of the Internal Medicine (Gastroenterology)


  • Professor of Medicine

    • Professor of gastroenterology Michigan Medicine Ann Arbor

    • Research focuses on diagnosis and treatment of functional bowel disorders and H. pylori infection

    • Medical innovator, holding several patents

    • Former co-editor-in-chief of The American Journal of Gastroenterology; authored more than 350 manuscripts

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